Grey’s Anatomy Season 21 Release Date, Trailer, Cast, Spoilers and News

ABC Network declared about release date of Grey's Anatomy season 22. Next part will be back on October 16, 2025. Read below fresh news and rumors about upcoming season.

Romance Medical Drama Television Series Grey's Anatomy started from March 27th, 2005 at ABC Network from United States. TV Series has 466 episodes in 22 seasons that aired every Thursday at 10 pm. It was created by Karin Gist (Co-Executive Producer) and James E. Williams (Producer).

New episodes comes out on Thursdays and has duration 60 minutes. Viewers grading series with average rating 7.7.

Contents:

1. The Plot
2. Season 22 Release Date
3. Cast
4. Schedule
5. Video Trailers

The Plot

Young surgeons want to make friends with each other but they also have the task of becoming the best intern. Therefore, they share their experiences with rivals, and try to get around other students. Meredith is the daughter of a famous surgeon, so everyone is biased towards her. She wants to get out of her father's shadow and is afraid to make mistakes, because gossips about her will quickly spread throughout the city. Christina has high expectations but she needs to learn how to be more polite and tactful with patients. Isobel has to work at once on two jobs, because she does not have money for training. But she will not exchange the surgeon's career for the position of model. George is a good student but he is afraid to start practicing; he is too unsure of himself.

Grey's Anatomy Season 22 Release Date

The ABC Channel is not yet announced what they will do with television series “Grey's Anatomy“. But by comparing with previous schedule, potential premiere date of Grey's Anatomy 22nd season is Thursday, October 16, 2025.

Grey’s Anatomy Season 22 Cast

Key roles in television series was played by Ellen Pompeo as Dr. Meredith Grey and James Pickens, Jr. as Dr. Richard Webber. Either Chandra Wilson (Dr. Miranda Bailey), Justin Chambers (Dr. Alex Karev), Kevin McKidd (Dr. Owen Hunt), Sara Ramirez (Dr. Calliope “Callie” Torres), Patrick Dempsey (Dr. Derek Shepherd), Jesse Williams (Dr. Jackson Avery), Sandra Oh (Dr. Cristina Yang) and Jessica Capshaw as Dr. Arizona Robbins.

Schedule for Grey's Anatomy Season 22

Trailers and Video Teasers

GREYS ANATOMY Season 22 Trailer | Release Date & FIRST LOOK